Antibody Quality Control
The highest priority is given to the quality of the generated antibodies. Since 1996, Davids has used established techniques for antibody development to produce the best possible antibodies. Davids often updated their procedures for antibody synthesis, vaccination, and purification during the previous decades to provide the greatest services. Quality control with ELISA, WesternBlot, and SDS-PAGE gels is performed on a regular basis to ensure consistent quality. Quality management systems are used in all of our services. If you have any further questions, please ask.
Own Animal Housing
Housing animals in our own department in Germany (Europe) ensures that all antibodies are made with animal protecting methods and healthy animals. Healthy animals have a strong immune system which leads to better antibodies. In addition we are able to respond to special wishes from our customers very fast.
Our animals receive daylight from roof-lights and additional light, when the daylight is low. The air is completely refreshed up to 25 times each hour. Our animals are grouped with 2 - 4 animals each, which lead to a nice interaction between the animals. Rabbits are able to stand, hide in a house, sit on a podest, eat hay and nibble on wood. Hen can sit on a stake, pick straw and hay and are able to scratch in straw and sand.
During the immunizations and taking of the blood samples the animals are not fixed. They are able to look around and discover the environment. The animals can see what is happening during the procedures.
All our good-natured handling with the animals lead to relaxed conditions with the result of non or low stressed animals and a fast immunization or blood sample. This is good for the animals and good for us as we save time altogether. In mind with non-stressed animals the antibodies are better.
Davids works in accordance with the 3R principle: Replacement (avoiding of animal experiments), Reduction (Limiting of the animal number) and Refinement (Enhance the living of the animals during the process).
Monoclonal Antibody Production in hybridoma, in vitro immunizations and cell culture based assays lead to a complete replacement of animals. In every case we try to limit the number of animals used for the immunization. Our standard offer is for the immunization of one animal as the anitbodies from one animal are in most cases enough for most applications. In combination with our high standards the difference of the immune response between two animals is very low, so the immunization of more than one animal is in most cases not necessary. For the production of a large amount of polyclonal antibodies we recommend chicken egg yolk antibodies. One chicken can replace up to 20 rabbits each year. Chicken egg yolk antibodies are additionally a refinement in mind, that no blood needs to be taken. The antibodies are collected from the eggs. Enrichment material for the animals leads to non-stressed animals that are used to the procedures and the animal carers.
Research & Development
Our own R&D department enables us to develop services and produce antibodies of highest quality and the possibility to serve our customers with personalized methods. We offer customized services according to the needs of our customers. All methods are developed to save resources and energy. That is good for the prices and our environment. All methods are frequently optimized for the use of environmental friendly substances and for the consumption of minimal energy. We have energy and resource saving technologies like energy saving freezers, refrigerators and artificial ventilation motors. Our housing is optimized to collect heat energy from the sun in winter, spring and autumn and to avoid heating in summer.
We do intensive research and developments in the field of cell based assays. This is to save time and money, make new test parameters possible, which cannot be measured otherwise. With the new technologies like in vitro immunizations we save animals and energy.
Our laboratory workers are using the newest technologies, which lead to improved methods and protocols. We educate new laboratory workers with great success. During the past, two of our employees finished their education as the best student of the year.
Our animal carers love animals, play with them and take care of them in the best way. The employees that are responsible for the animals have a FELASA certificate.
Our office is managed by competent employees, who provide you with fast offers and good prices and who support you for scientific questions.
We do not employ field workers and we do not present us in exhibitions. In combination with a small bureaucracy, this lead to time and money saving processes and to good prices for our customers.
Confidentiality & Security
All customer data is handled confidential. This includes customer names, address, antigen, material from customer or material that we produced for our customers. Please find a detailed information here: Privacy Notice. For this reason we do not give any references to customers. There are a lot of publications, that uses antibodies from Davids Biotechnologie GmbH, but we do not keep track of the publications as not every customer gives a feedback to us when he uses our name in the publication. When you are interested in antibodies from Davids that were used in research, you can search for "Davids Biotechnologie" in your favourite site that provides you with scientific articles.
All data is secured and saved in a secure place. Critical information is encrypted before saved in the database.